"The only way to unravel the marvel that is the human heart is to find the One who made it!"
Sri Sathya Sai Sanjeevani Research Foundation (SSSSRF) is a DSIR recognised Scientific and Industrial Research Organization (SIRO) established to pursue research in Congenital Heart Disease (CHD). A charitable foundation (Darpan No. KA/2017/0154544) with 12A & 80G certification.
Vision: "To Understand and Contribute to Life through the pursuit of Advanced Human Genomics Research in Congenital Heart Diseases"
Congenital Heart Defects account for 28% of all birth defects and are among the leading causes of infant mortality in India. Investigating the genetic and epigenetic basis of CHD is essential for primary prevention.
Dr. C. Sreenivas has been associated with Bhagawan Sri Sathya Sai Baba and His various Service Projects in Healthcare, Education, and Rural Service Initiatives for over 40 years. He has built and run the Sri Sathya Sai Sanjeevani Hospitals — Centres for Child Heart Care — wherein all services are provided Totally Free of Cost to all.
The Foundation shall bring together Scientists, Clinicians, and Public Health Experts to holistically address Mother & Child Health and Congenital Heart Disease.
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Padmashree Dr. K.M. Cherian visited SSSSRF
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Research Team with Prof. Dr. M.S. Valiathan, 2019
3rd IEC Meet, November 2019
Research Activity at Palwal Centre
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DSIR Recognised Scientific & Industrial Research Organisation
Sri Sathya Sai Sanjeevani Research Foundation (SSSSRF) is a DSIR recognised Scientific and Industrial Research Organization (SIRO) established with a purpose to pursue research in Congenital Heart Disease (CHD). This is a charitable foundation (Darpan Registration No. KA/2017/0154544) with 12A & 80G certification.
SSSSRF was registered on 22nd March 2018 at Bangalore with its operational research centres inaugurated on 7th June 2018 in Palwal and on 23rd August 2022 in Kharghar, Navi Mumbai. We are also functional at Atal Nagar (Naya Raipur), Chhattisgarh.
The strength of SSSSRF is its collaboration with Sri Sathya Sai Sanjeevani Pediatric Cardiac Hospitals which are dedicated centres for treatment of Congenital Heart Disease. At SSSSRF, we investigate factors impacting incidence of CHD by understanding the genetic and epigenetic basis of CHD.
Our mission: to contribute to societal welfare by achieving 'Healthy Childhood' through prevention of CHD.
"To Understand and Contribute to Life through the pursuit of Advanced Human Genomics Research in Congenital Heart Diseases"
To contribute to societal welfare by achieving 'Healthy Childhood' through primary prevention of CHD.
Dr. C. Sreenivas has been associated with Bhagawan Sri Sathya Sai Baba and His various Service Projects in Healthcare, Education, Drinking Water Supply and Rural Service Initiatives for over 40 years. A selfless worker; he has built and run several Institutions of Service most notably the Sri Sathya Sai Sanjeevani Hospitals — Centres for Child Heart Care, wherein all services are provided Totally Free of Cost to all.
Sri Madhusudan Sai is an educationist, philanthropist and a social entrepreneur who has built and run University, Schools and various Health Projects in India and abroad with all services provided Totally Free of Cost.
Sri. Balasubramanian Athmanathan is CEO of Aditya Birla Sun Life Asset Management Company Limited and is actively involved in various social projects in the field of Education, Healthcare and Nutrition.
Eminent scientists and clinicians guiding SSSSRF research
India's National CHD Biorepository
Congenital Heart Defects (CHDs) are amongst the leading causes of infant mortality comprising of 28% of all birth defects. At Sri Sathya Sai Sanjeevani Hospital, diverse spectrum of CHD cases from all religions, caste and creed are treated totally free of cost. This high magnitude and diversity is an extremely rich resource in CHD research. Invaluable biological samples can be stored systematically in a Biorepository.
To build national biorepository for CHD in India to aid research towards bringing down the incidence of CHD.
Build national biorepository for CHD in India.
Develop skilled manpower in biobanking through training.
Collect biological samples (blood, serum, plasma, urine, saliva, buccal swab) from CHD patients, parents and available relatives.
Collect samples from healthy controls including parents and healthy relatives.
Compile detailed case history and environmental causal factor data into a registry.
Explore sample storage aspects with scientific significance for efficient QA-QC measures.
National capacity building in CHD research through training and services.
Spread awareness about the importance, need and science of Biobanking in India.
Three primary themes addressing the aetiology of Congenital Heart Disease
Joshi RO, Kukshal P, Chellappan S, Guhathakurta S. The study of expression levels of DNA methylation regulators in patients affected with congenital heart defects (CHDs). Birth Defects Research. 2022;1–10.
Chellappan S, Manohar K, Sathe Y, James A, Joshi R, Hamza A. Pseudoaneurysm following a neonatal coarctation repair; a dreadful complication. Asian Cardiovascular & Thoracic Annals 2021;1–7.
Chellappan S, Manohar K, Sathe Y, Amboli S, Joshi R, Hiremath N. Isolated left subclavian with a compensatory ductus in a child with Tetralogy of Fallot. Asian Cardiovascular & Thoracic Annals 2021;0(0):1–3.
Chellappan S, Manohar K, Sathe Y, Pandey R, Joshi R, Deshpande A. Acyanotic Truncus Arteriosus: Not a Misnomer But a True Rarity. World Journal of Paediatric and Congenital Heart Surgery; DOI: 10.1177/21501351211000367.
Joshi RO, Chellappan S, Kukshal P. Exploring the Role of Maternal Nutritional Epigenetics in Congenital Heart Disease. Curr Dev Nutr 2020;4:nzaa166.
Chellappan S, Soman KR, Sathe Y, Kukshal P, James A. Transesophageal Echocardiography Reveals a Missed Right Atrial Aneurysm in a Patient with Atrial Septal Defect and Mitral Valve Prolapse. J Cardiovasc Echogr. 2020 Jul-Sep;30(3):171–173.
For the complete publication list, contact the research team.
National and international research partnerships
We are open for research collaborations. Contact: info@ssssrf.org
Research training at Palwal and Kharghar in Genomics & Molecular Biology
Undergraduate in Life Science / Biotechnology / Botany / Zoology or Diploma in Medical Laboratory Technology.
Hands-on experience in genomics and molecular biology laboratory techniques.
Masters in Life Science / Biotechnology.
Post-graduate dissertation research in CHD genomics and molecular biology at SSSSRF.
Applications can be sent to the Laboratory in charge throughout the year. There will be an initial scrutiny by selection committee and shortlisted candidates will be called for personal interview.
Write to: researchcentre@srisathyasaisanjeevani.com — upload your CV along with your area of interest.
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Your contribution — in any form — advances our mission of preventing Congenital Heart Disease through genomic research.
Fund genomic research that saves children's lives. 80G tax exemption for Indian donors. FCRA registered for international donors.
We welcome collaboration proposals from scientists and research institutions nationally and internationally.
Join our research team. Current opening: Bioinformatician at Palwal, Haryana.
Short-term (2–3 months) and dissertation (6 months) training in Genomics & Molecular Biology.
All treatment at Sri Sathya Sai Sanjeevani Hospitals is provided Totally Free of Cost to every patient. Your donation funds cutting-edge genomic research to understand and prevent CHD.
Indian donors are eligible for tax exemption under Section 80G. FCRA registered for international donations.
Contact us with your contribution details and we will guide you through the process:
"Healthcare is complete when treatment of disease is accompanied by the understanding of its causes."
We welcome collaboration proposals from scientists and research institutions nationally and internationally. Write to us with your proposal and areas of research synergy.
info@ssssrf.org →Interested in joining SSSSRF? Send your CV with a brief statement of research interest. We review applications on a rolling basis.
Send CV →Write to info@ssssrf.org or hr.palwal@ssssrf.org with your CV and brief statement of interest.
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